Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

نویسندگان

  • Alexander C. Aichelburg
  • Julia Walochnik
  • Ojan Assadian
  • Helmut Prosch
  • Andrea Steuer
  • Gedeon Perneczky
  • Govinda S. Visvesvara
  • Horst Aspöck
  • Norbert Vetter
چکیده

We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation.

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Anti-acanthamoeba efficacy and toxicity of miltefosine in an organotypic skin equivalent.

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عنوان ژورنال:
  • Emerging Infectious Diseases

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2008